Pub. Date : 2011 Sep
PMID : 21775527
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, BMDM treated with inhibitors of PPARgamma and STAT6, pivotal transcription factors that mediate the activity of Se and IL-4, respectively, showed complete ablation of Se-dependent expression of M2 markers. | Selenium | peroxisome proliferator activated receptor gamma | Mus musculus |
| 2 | In summary, these studies suggest that Se supplementation of macrophages produces endogenous activators to mediate the PPARgamma-dependent switch from M1 to M2 phenotype in the presence of IL-4, possibly affecting pathways of wound healing and inflammation resolution. | Selenium | peroxisome proliferator activated receptor gamma | Mus musculus |