Title : Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity: studies with gemifloxacin, moxifloxacin and ciprofloxacin in a pharmacokinetic/pharmacodynamic model of uninfected and infected macrophages.

Pub. Date : 2011 Sep

PMID : 21764262






1 Functional Relationships(s)
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1 Using murine J774 macrophages and human THP-1 monocytes, we show that gemifloxacin accumulates more than ciprofloxacin and even moxifloxacin. Gemifloxacin GLI family zinc finger 2 Homo sapiens