Title : Cholangiocyte N-Ras protein mediates lipopolysaccharide-induced interleukin 6 secretion and proliferation.

Pub. Date : 2011 Sep 2

PMID : 21757746






1 Functional Relationships(s)
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1 Using a luciferase reporter, we demonstrated that LPS treatment induced IL6 promoter-driven luciferase which was suppressed using MEK/ERK pharmacologic inhibitors (PD98059 or U0126) and RNAi-induced depletion of N-Ras. U 0126 interleukin 6 Homo sapiens