Pub. Date : 2011 Sep
PMID : 21752898
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glucose ingestion selectively amplifies ACTH and cortisol secretory-burst mass and enhances their joint synchrony in healthy men. | Glucose | proopiomelanocortin | Homo sapiens |
| 2 | HYPOTHESIS: Glucose ingestion elevates cortisol secretion by 1) augmenting pulsatile ACTH release; and/or 2) enhancing ACTH-cortisol synchrony or dose-responsiveness. | Glucose | proopiomelanocortin | Homo sapiens |
| 3 | HYPOTHESIS: Glucose ingestion elevates cortisol secretion by 1) augmenting pulsatile ACTH release; and/or 2) enhancing ACTH-cortisol synchrony or dose-responsiveness. | Glucose | proopiomelanocortin | Homo sapiens |
| 4 | Glucose ingestion abolished both relationships but amplified pulsatile ACTH (P = 0.009) and cortisol (P = 0.001) secretion. | Glucose | proopiomelanocortin | Homo sapiens |
| 5 | Glucose exposure selectively augmented the mass of ACTH (P < 0.001) and of cortisol (P = 0.004) secreted per burst without altering burst number or basal secretion. | Glucose | proopiomelanocortin | Homo sapiens |
| 6 | According to approximate entropy analysis, glucose input also enhanced the joint synchrony of ACTH-cortisol secretory patterns (P <= 0.001). | Glucose | proopiomelanocortin | Homo sapiens |
| 7 | CONCLUSION: Conjoint augmentation of the mass of ACTH and cortisol secreted per burst and enhancement of ACTH-cortisol synchrony underlie glucose-induced glucocorticoid secretion in healthy men. | Glucose | proopiomelanocortin | Homo sapiens |
| 8 | CONCLUSION: Conjoint augmentation of the mass of ACTH and cortisol secreted per burst and enhancement of ACTH-cortisol synchrony underlie glucose-induced glucocorticoid secretion in healthy men. | Glucose | proopiomelanocortin | Homo sapiens |