Title : UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model.

Pub. Date : 2011 Sep 2

PMID : 21749142






2 Functional Relationships(s)
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1 UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model. 3-phenyllactic acid peroxisome proliferator activated receptor alpha Mus musculus
2 However, increased excretion of indole-3-lactic acid and phenyllactic acid was found to be a conserved feature exclusively associated with the alcohol-treated Ppara-null mouse on both backgrounds that develop liver pathologies similar to the early stages of human ALD. 3-phenyllactic acid peroxisome proliferator activated receptor alpha Mus musculus