Title : Local constraints in either the GluN1 or GluN2 subunit equally impair NMDA receptor pore opening.

Pub. Date : 2011 Aug

PMID : 21746848






1 Functional Relationships(s)
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Organism
1 NMDA receptors are obligate heterotetramers typically composed of glycine-binding GluN1 and glutamate-binding GluN2 subunits that gate in a concerted fashion, requiring all four ligands to bind for subsequent opening of the channel pore. Glycine glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens