Title : Carbonic anhydrase I and II activation with mono- and dihalogenated histamine derivatives.

Pub. Date : 2011 Aug 15

PMID : 21742491






1 Functional Relationships(s)
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1 Low nanomolar and subnanomolar hCA I and II activators have been detected for the first time, starting from histamine as lead which has an affinity of 2 muM against isoform I and of 125 muM against hCA II. Histamine carbonic anhydrase 2 Homo sapiens