PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21742491-4 2011 Low nanomolar and subnanomolar hCA I and II activators have been detected for the first time, starting from histamine as lead which has an affinity of 2 muM against isoform I and of 125 muM against hCA II. Histamine 108-117 carbonic anhydrase 2 Homo sapiens 198-204