Pub. Date : 2011 Sep 15
PMID : 21723941
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tocotrienols inhibit AKT and ERK activation and suppress pancreatic cancer cell proliferation by suppressing the ErbB2 pathway. | Tocotrienols | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Our results suggest that the tocotrienol isoforms of vitamin E can induce apoptosis in pancreatic cancer cells through the suppression of vital cell survival and proliferative signaling pathways such as those mediated by the PI3-kinase/AKT and ERK/MAP kinases via downregulation of Her2/ErbB2 expression. | Tocotrienols | mitogen-activated protein kinase 1 | Homo sapiens |