Title : Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes.

Pub. Date : 2011 Oct 9

PMID : 21723365






1 Functional Relationships(s)
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1 The biological activity of PFOA and PFOS in rodents is attributed primarily to transactivation of the nuclear receptor peroxisome proliferator activated receptor alpha (PPARA), which is an important regulator of lipid and carbohydrate metabolism. Carbohydrates peroxisome proliferator activated receptor alpha Homo sapiens