Title : Angiotensin II activation of mTOR results in tubulointerstitial fibrosis through loss of N-cadherin.

Pub. Date : 2011

PMID : 21720156






1 Functional Relationships(s)
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1 METHODS: We utilized young transgenic Ren2 rats (R2-T) and Sprague-Dawley rats (SD-T) treated with the Ang type 1 receptor (AT(1)R) blocker telmisartan (2 mg kg(-1) day(-1)) or vehicle (R2-C; SD-C) for 3 weeks to examine PT structure and function. Telmisartan angiotensin II receptor, type 1a Rattus norvegicus