Title : Activation of peroxisome proliferator-activated receptor-{delta} enhances regenerative capacity of human endothelial progenitor cells by stimulating biosynthesis of tetrahydrobiopterin.

Pub. Date : 2011 Aug

PMID : 21709207






1 Functional Relationships(s)
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1 Thus, in human EPCs, activation of PPARdelta stimulates expression and activity of GTPCH I and biosynthesis of tetrahydrobiopterin via PTEN-AKT signaling pathway. sapropterin phosphatase and tensin homolog Homo sapiens