Title : Activation of intracellular pathways with forskolin and phorbol ester increases LHRH mRNA level in the rat hypothalamus superfused in vitro.

Pub. Date : 1990 Aug

PMID : 2170797






3 Functional Relationships(s)
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1 In vitro perfusion of hypothalamic fragments with PMA and/or FKN stimulated LHRH release as well as LHRH mRNA. Tetradecanoylphorbol Acetate gonadotropin releasing hormone 1 Rattus norvegicus
2 In vitro perfusion of hypothalamic fragments with PMA and/or FKN stimulated LHRH release as well as LHRH mRNA. Tetradecanoylphorbol Acetate gonadotropin releasing hormone 1 Rattus norvegicus
3 The combined infusion of FKN and PMA did not produce an additive effect on the LHRH mRNA levels, but it was effective in synergistically increasing LHRH secretion in vitro. Tetradecanoylphorbol Acetate gonadotropin releasing hormone 1 Rattus norvegicus