Title : Occupancy of both sites on the thyrotropin (TSH) receptor dimer is necessary for phosphoinositide signaling.

Pub. Date : 2011 Oct

PMID : 21705666






3 Functional Relationships(s)
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1 When L252P or C41S was expressed with TSHR, that is, when TSHR/L252P or TSHR/C41S heterodimers could only bind one TSH, TSH-stimulated IP1 production was decreased relative to cAMP production. Thyrotropin thyroid stimulating hormone receptor Homo sapiens
2 When L252P or C41S was expressed with TSHR, that is, when TSHR/L252P or TSHR/C41S heterodimers could only bind one TSH, TSH-stimulated IP1 production was decreased relative to cAMP production. Thyrotropin thyroid stimulating hormone receptor Homo sapiens
3 When L252P or C41S was expressed with TSHR, that is, when TSHR/L252P or TSHR/C41S heterodimers could only bind one TSH, TSH-stimulated IP1 production was decreased relative to cAMP production. Thyrotropin thyroid stimulating hormone receptor Homo sapiens