Protein Name thyroid stimulating hormone receptor
Organism Homo sapiens
Gene ID 7253
Gene Symbol

TSHR

UniProt P16473 (TSHR_HUMAN), A0A0A0MTJ0 (A0A0A0MTJ0_HUMAN)
Relationships Total Number of functionally related compound(s) : 302
Total Number of Articles : 726
Description

thyroid stimulating hormone receptor

Gene Summary

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

synonyms
  • thyrotropin receptor
  • TSH receptor
  • seven transmembrane helix receptor
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Properties