Pub. Date : 2011
PMID : 21695637
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclic nucleotide phosphodiesterases (PDEs) share a highly conserved catalytic domain that hydrolyzes cAMP, cGMP, or both nucleotides. | Cyclic AMP | phosphodiesterase 10A | Homo sapiens |
| 2 | In addition, the structures of PDE10A in complex with cAMP and cGMP reveal that cAMP and cGMP bind to the active site in different orientations and have different interactions with PDE10A residues. | Cyclic AMP | phosphodiesterase 10A | Homo sapiens |
| 3 | In addition, the structures of PDE10A in complex with cAMP and cGMP reveal that cAMP and cGMP bind to the active site in different orientations and have different interactions with PDE10A residues. | Cyclic AMP | phosphodiesterase 10A | Homo sapiens |
| 4 | In addition, the structures of PDE10A in complex with cAMP and cGMP reveal that cAMP and cGMP bind to the active site in different orientations and have different interactions with PDE10A residues. | Cyclic AMP | phosphodiesterase 10A | Homo sapiens |
| 5 | In addition, the structures of PDE10A in complex with cAMP and cGMP reveal that cAMP and cGMP bind to the active site in different orientations and have different interactions with PDE10A residues. | Cyclic AMP | phosphodiesterase 10A | Homo sapiens |