Protein Name phosphodiesterase 10A
Organism Homo sapiens
Gene ID 10846
Gene Symbol

PDE10A

UniProt Q9Y233 (PDE10_HUMAN), A0A1B1UZQ1 (A0A1B1UZQ1_HUMAN), A0A1B1UZR0 (A0A1B1UZR0_HUMAN)
Relationships Total Number of functionally related compound(s) : 138
Total Number of Articles : 137
Description

phosphodiesterase 10A

Gene Summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]

synonyms
  • cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  • 3',5' cAMP/cGMP phosphodiesterase
  • dJ416F21.1 (phosphodiesterase 10A)
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Properties