Title : Anti-neoplastic action of aspirin against a T-cell lymphoma involves an alteration in the tumour microenvironment and regulation of tumour cell survival.

Pub. Date : 2012 Feb

PMID : 21692746






1 Functional Relationships(s)
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1 Intratumoral administration of aspirin was accompanied by alterations in the biophysical, biochemical and immunological composition of the tumour microenvironment with respect to pH, level of dissolved O2, glucose, lactate, nitric oxide, IFNgamma (interferon gamma), IL-4 (interleukin-4), IL-6 and IL-10, whereas the TGF-beta (tumour growth factor-beta) level was unaltered. Aspirin interleukin 6 Mus musculus