Pub. Date : 2011 Jul 15
PMID : 21689633
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hyperoside further enhanced the cellular antioxidant defense system through increasing the activity of heme oxygenase-1 (HO-1), and by up-regulating HO-1 expression. | hyperoside | heme oxygenase 1 | Homo sapiens |
| 2 | Hyperoside further enhanced the cellular antioxidant defense system through increasing the activity of heme oxygenase-1 (HO-1), and by up-regulating HO-1 expression. | hyperoside | heme oxygenase 1 | Homo sapiens |
| 3 | Hyperoside further enhanced the cellular antioxidant defense system through increasing the activity of heme oxygenase-1 (HO-1), and by up-regulating HO-1 expression. | hyperoside | heme oxygenase 1 | Homo sapiens |
| 4 | Collectively, our data provide the first description of the mechanism underlying hyperoside"s ability to attenuate H(2)O(2)-induced cell damage, namely this compound interacts with the MAPK-dependent Keap(1)-Nrf(2)-ARE signaling pathway to up-regulate HO-1 expression and enhance intracellular antioxidant activity. | hyperoside | heme oxygenase 1 | Homo sapiens |