Title : Bezafibrate prevents palmitate-induced apoptosis in osteoblastic MC3T3-E1 cells through the NF-κB signaling pathway.

Pub. Date : 2011 Oct

PMID : 21687928

1 Functional Relationships(s)
Compound Name
Protein Name
1 We observed that bezafibrate, a dual ligand for the peroxisome proliferator-activated receptors alpha (PPARalpha) and PPARdelta, significantly attenuated the palmitate-induced cytotoxicity as determined by the MTT assay and inhibited the palmitate-induced apoptosis as determined by a flow cytometry assay using Annexin V-FITC/PI and assessment of the activity of caspase-3. Palmitates peroxisome proliferator activator receptor delta Mus musculus