Pub. Date : 2011 Jul 6
PMID : 21685359
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer. | Niclosamide | S100 calcium binding protein A4 | Mus musculus |
| 2 | RESULTS: Reduced S100A4 mRNA and protein expression, and inhibited cell migration, invasion, proliferation, and colony formation were observed in niclosamide-treated colon cancer cells in vitro. | Niclosamide | S100 calcium binding protein A4 | Mus musculus |
| 3 | CONCLUSION: Niclosamide inhibits S100A4-induced metastasis formation in a mouse model of colon cancer and has therapeutic potential. | Niclosamide | S100 calcium binding protein A4 | Mus musculus |