Pub. Date : 2012 Mar
PMID : 21681430
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Little is known about the concomitant presence of the ACE gene D allele and paraoxonase (PON1) codon 192 arginine (Arg) on the severity of CAD. | Arginine | paraoxonase 1 | Homo sapiens |
| 2 | Little is known about the concomitant presence of the ACE gene D allele and paraoxonase (PON1) codon 192 arginine (Arg) on the severity of CAD. | Arginine | paraoxonase 1 | Homo sapiens |
| 3 | Regarding the high rate of CAD among Iranians the aim of present study was to examine the hypothesis of synergistic effects between ACE-D and PON1-Arg alleles on predisposition and the severity of CAD in our population. | Arginine | paraoxonase 1 | Homo sapiens |
| 4 | We found that PON1 Arg 192 and ACE D allele act synergistically to increase the risk of CAD (OR 1.3, P = 0.044). | Arginine | paraoxonase 1 | Homo sapiens |
| 5 | Our results showed a significant correlation between the possession of both PON1 192 Arg and the ACE D allele and the extent of CAD in CAD patients and CAD subjects without diabetes, represented by the increased frequency of three-vessel disease with OR 2.7, P = 0.046; chi(2) = 4, P = 0.046 and OR 2.4, P = 0.051; chi(2) = 3.8, P = 0.051, respectively. | Arginine | paraoxonase 1 | Homo sapiens |
| 6 | We found that PON1 Arg 192 and ACE D alleles act synergistically to increase the risk of CAD in CAD patients and CAD subjects without diabetes from west of Iran, who have high frequency of three-vessel disease. | Arginine | paraoxonase 1 | Homo sapiens |
| 7 | Our data suggest that PON1 192 Arg and the ACE D allele in combination with each other can be important independent risk factor for severity of CAD in patients carrying both PON1 192 Arg and the ACE D allele in a west population of Iran. | Arginine | paraoxonase 1 | Homo sapiens |
| 8 | Our data suggest that PON1 192 Arg and the ACE D allele in combination with each other can be important independent risk factor for severity of CAD in patients carrying both PON1 192 Arg and the ACE D allele in a west population of Iran. | Arginine | paraoxonase 1 | Homo sapiens |
| 9 | Our data suggest that PON1 192 Arg and the ACE D allele in combination with each other can be important independent risk factor for severity of CAD in patients carrying both PON1 192 Arg and the ACE D allele in a west population of Iran. | Arginine | paraoxonase 1 | Homo sapiens |
| 10 | Our data suggest that PON1 192 Arg and the ACE D allele in combination with each other can be important independent risk factor for severity of CAD in patients carrying both PON1 192 Arg and the ACE D allele in a west population of Iran. | Arginine | paraoxonase 1 | Homo sapiens |