Title : Metformin: a new option in cancer treatment.

Pub. Date : 2011 Jun

PMID : 21680296






2 Functional Relationships(s)
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1 Metformin activates the AMP-activated protein kinase (AMPK) pathway, a major sensor of the energy status of the cell and an inhibitor of mammalian target of rapamycin (mTOR) catalytic activity, inducing a decrease in blood glucose by decreasing hepatic gluconeogenesis and stimulating glucose uptake in the muscle. Metformin mechanistic target of rapamycin kinase Homo sapiens
2 Metformin activates the AMP-activated protein kinase (AMPK) pathway, a major sensor of the energy status of the cell and an inhibitor of mammalian target of rapamycin (mTOR) catalytic activity, inducing a decrease in blood glucose by decreasing hepatic gluconeogenesis and stimulating glucose uptake in the muscle. Metformin mechanistic target of rapamycin kinase Homo sapiens