Pub. Date : 2011 Sep
PMID : 21653710
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine excites hypothalamic arcuate anorexigenic proopiomelanocortin neurons and orexigenic neuropeptide Y neurons: similarities and differences. | Nicotine | proopiomelanocortin | Homo sapiens |
| 2 | Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus, nicotine should excite these cells. | Nicotine | proopiomelanocortin | Homo sapiens |
| 3 | Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus, nicotine should excite these cells. | Nicotine | proopiomelanocortin | Homo sapiens |
| 4 | Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus, nicotine should excite these cells. | Nicotine | proopiomelanocortin | Homo sapiens |
| 5 | Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus, nicotine should excite these cells. | Nicotine | proopiomelanocortin | Homo sapiens |
| 6 | Nicotine at concentrations similar to those found in smokers, 100-1,000 nM, excited POMC cells by mechanisms based on increased spike frequency, depolarization of membrane potential, and opening of ion channels. | Nicotine | proopiomelanocortin | Homo sapiens |
| 7 | Nicotine exerted similar actions on POMC and NPY cells, with a slightly greater depolarizing action on POMC cells. | Nicotine | proopiomelanocortin | Homo sapiens |
| 8 | Nicotine exerted similar actions on POMC and NPY cells, with a slightly greater depolarizing action on POMC cells. | Nicotine | proopiomelanocortin | Homo sapiens |
| 9 | Together, these results indicate that nicotine has a number of similar actions, but also a few different actions, on POMC and NPY neurons that could contribute to the weight loss associated with smoking. | Nicotine | proopiomelanocortin | Homo sapiens |