PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21653710-0	2011	Nicotine excites hypothalamic arcuate anorexigenic proopiomelanocortin neurons and orexigenic neuropeptide Y neurons: similarities and differences.	Nicotine	0-8	proopiomelanocortin	Homo sapiens	51-70	
21653710-3	2011	Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus, nicotine should excite these cells.	Nicotine	66-74	proopiomelanocortin	Homo sapiens	104-123	
21653710-3	2011	Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus, nicotine should excite these cells.	Nicotine	66-74	proopiomelanocortin	Homo sapiens	125-129	
21653710-3	2011	Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus, nicotine should excite these cells.	Nicotine	176-184	proopiomelanocortin	Homo sapiens	104-123	
21653710-3	2011	Here we address the hypothesis that if weight-reducing actions of nicotine are mediated by anorexigenic proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus, nicotine should excite these cells.	Nicotine	176-184	proopiomelanocortin	Homo sapiens	125-129	
21653710-4	2011	Nicotine at concentrations similar to those found in smokers, 100-1,000 nM, excited POMC cells by mechanisms based on increased spike frequency, depolarization of membrane potential, and opening of ion channels.	Nicotine	0-8	proopiomelanocortin	Homo sapiens	84-88	
21653710-7	2011	Nicotine exerted similar actions on POMC and NPY cells, with a slightly greater depolarizing action on POMC cells.	Nicotine	0-8	proopiomelanocortin	Homo sapiens	36-40	
21653710-7	2011	Nicotine exerted similar actions on POMC and NPY cells, with a slightly greater depolarizing action on POMC cells.	Nicotine	0-8	proopiomelanocortin	Homo sapiens	103-107	
21653710-13	2011	Together, these results indicate that nicotine has a number of similar actions, but also a few different actions, on POMC and NPY neurons that could contribute to the weight loss associated with smoking.	Nicotine	38-46	proopiomelanocortin	Homo sapiens	117-121