Title : Prazosin induces p53-mediated autophagic cell death in H9C2 cells.

Pub. Date : 2011 Aug

PMID : 21614555






1 Functional Relationships(s)
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1 Western blot analysis of phosphorylated proteins showed that exposure to prazosin increased the levels of phospho-p53 and phospho-adenosine monophosphate-activated protein kinase (AMPK) but dramatically decreased the levels of phospho-mammalian target of rapamycin (mTOR), phospho-protein kinase B (Akt), and phospho-ribosomal protein S6 kinase (p70S6K). Prazosin ribosomal protein S6 kinase B1 Homo sapiens