Title : Sphingosine-1-phosphate acting via the S1P₁ receptor is a downstream signaling pathway in ceramide-induced hyperalgesia.

Pub. Date : 2011 Jul 15

PMID : 21605625






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 Once generated, ceramide is converted by sphingosine kinase (SphK) 1 and/or 2 to one of its active metabolite sphingosine-1-phosphate (S1P), which in turn signals through G-protein coupled S1P receptors. Ceramides sphingosine kinase 1 Rattus norvegicus