PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21605625-2 2011 Once generated, ceramide is converted by sphingosine kinase (SphK) 1 and/or 2 to one of its active metabolite sphingosine-1-phosphate (S1P), which in turn signals through G-protein coupled S1P receptors. Ceramides 16-24 sphingosine kinase 1 Rattus norvegicus 41-68