Pub. Date : 2011 Sep
PMID : 21586345
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fluorofenidone significantly reduced Ang II-induced increases in Fas, FasL, Bax, Caspase-8 and Caspase-3 at the mRNA level. | 5-methyl-1-(3-fluorophenyl)-2-(1H)-pyridone | caspase 3 | Rattus norvegicus |
| 2 | Additionally, Ang II-induced activation of Caspase-8 and Caspase-3 as well as Ang II-initiated downregulation of Bcl-2 at both mRNA and protein levels was all prevented by fluorofenidone. | 5-methyl-1-(3-fluorophenyl)-2-(1H)-pyridone | caspase 3 | Rattus norvegicus |