Title : Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest.

Pub. Date : 2012 Aug

PMID : 21573958






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Sal treatment also reduced p21 levels in radiation-treated cells. salinomycin H3 histone pseudogene 16 Homo sapiens
2 Considering that Sal sensitizes doxorubicin (DOX)- or etoposide (ETO)-treated cancer cells by causing DNA damage and reducing p21 expression, the results from our study suggest that the mechanism underlying Sal sensitization is conserved in both chemo- and radiation-treated cells. salinomycin H3 histone pseudogene 16 Homo sapiens
3 Considering that Sal sensitizes doxorubicin (DOX)- or etoposide (ETO)-treated cancer cells by causing DNA damage and reducing p21 expression, the results from our study suggest that the mechanism underlying Sal sensitization is conserved in both chemo- and radiation-treated cells. salinomycin H3 histone pseudogene 16 Homo sapiens