Pub. Date : 2011 Sep
PMID : 21570990
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sensitized activation of Fos and brain-derived neurotrophic factor in the medial prefrontal cortex and ventral tegmental area accompanies behavioral sensitization to amphetamine. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | Amphetamine challenge increased Fos and BDNF expression in the mPFC regardless of prior drug experience, and further augmented mPFC BDNF expression in sensitized rats. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | Similarly, more Fos-FG and Fos-BDNF double-labeling was observed in the mPFC of sensitized rats compared to drug-naive rats after amphetamine challenge. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 4 | Similarly, more Fos-FG and Fos-BDNF double-labeling was observed in the mPFC of sensitized rats compared to drug-naive rats after amphetamine challenge. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 5 | Repeated amphetamine treatment also increased VTA BDNF, while both acute and repeated amphetamine treatment increased Fos and Fos-BDNF co-labeling, an effect enhanced in sensitized rats. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 6 | Repeated amphetamine treatment also increased VTA BDNF, while both acute and repeated amphetamine treatment increased Fos and Fos-BDNF co-labeling, an effect enhanced in sensitized rats. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |