Pub. Date : 2011 May 24
PMID : 21555592
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we demonstrate that pharmacological inhibition of Mcl-1 expression with the unique Apogossypol derivative BI-97C1, also called Sabutoclax, is sufficient to sensitize prostate tumors to mda-7/IL-24-induced apoptosis, whereas ABT-737, which lacks efficacy in inhibiting Mcl-1, does not sensitize mda-7/IL-24-mediated cytotoxicity. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |