Pub. Date : 2011 Jul 1
PMID : 21550982
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MALDI-TOF-MS analysis of peptides harboring site-directed substitutions of cysteine with histidine residues within the PARP-1 zinc finger revealed that arsenite bound to peptides containing three or four cysteine residues, but not to peptides with two cysteines, demonstrating arsenite binding selectivity. | Cysteine | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 2 | MALDI-TOF-MS analysis of peptides harboring site-directed substitutions of cysteine with histidine residues within the PARP-1 zinc finger revealed that arsenite bound to peptides containing three or four cysteine residues, but not to peptides with two cysteines, demonstrating arsenite binding selectivity. | Cysteine | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 3 | These findings demonstrate that PARP-1 is a direct molecular target of arsenite and that arsenite interacts selectively with zinc finger motifs containing three or more cysteine residues. | Cysteine | poly(ADP-ribose) polymerase 1 | Homo sapiens |