Title : Spinal protein kinase M ΞΆ underlies the maintenance mechanism of persistent nociceptive sensitization.

Pub. Date : 2011 May 4

PMID : 21543593






2 Functional Relationships(s)
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Protein Name
Organism
1 Intraplantar injection of IL-6 followed immediately by intrathecal injection of a PKMzeta inhibitor prevented the expression of subsequent PGE(2)-induced allodynia. Dinoprostone interleukin 6 Mus musculus
2 Inhibitors of protein translation were effective in preventing PGE(2)-induced allodynia when given immediately after IL-6, but not after the initial allodynia had resolved. Dinoprostone interleukin 6 Mus musculus