Title : Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy.

Pub. Date : 1996 Dec

PMID : 21541623






1 Functional Relationships(s)
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1 As a cytostatic mechanism, however, Flavopiridol strongly inhibits the cyclin-dependent kinases (cdk1, cdk2, cdk4, cdk7), with the potential to cause inhibition of cell cycle progression in G(1) and G(2) by multiple mechanisms relatable to cdk inhibition. alvocidib cyclin dependent kinase 1 Homo sapiens