Title : Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-κB.

Pub. Date : 2011 Aug

PMID : 21520490






1 Functional Relationships(s)
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1 Blocking of RES-induced apoptosis in EL4 cells by FasL mAb, cleavage of caspases and PARP, and release of cytochorme c, demonstrated the participation of both extrinsic and intrinsic pathways of apoptosis. Resveratrol poly (ADP-ribose) polymerase family, member 1 Mus musculus