Pub. Date : 2012 Mar
PMID : 21497499
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Piceatannol inhibits migration and invasion of prostate cancer cells: possible mediation by decreased interleukin-6 signaling. | 3,3',4,5'-tetrahydroxystilbene | interleukin 6 | Homo sapiens |
| 2 | Interleukin-6 treatment was also shown to enhance the secretion of uPA and VEGF, STAT3 phosphorylation and the migration of DU145 cells; these increases were suppressed by piceatannol. | 3,3',4,5'-tetrahydroxystilbene | interleukin 6 | Homo sapiens |
| 3 | These results demonstrate that the inhibition of IL-6/STAT3 signaling may constitute a mechanism by which piceatannol regulates the expression of proteins involved in regulating the migration and invasion of DU145 cells. | 3,3',4,5'-tetrahydroxystilbene | interleukin 6 | Homo sapiens |