Title : Naturally occurring autoantibodies against beta-amyloid: investigating their role in transgenic animal and in vitro models of Alzheimer's disease.

Pub. Date : 2011 Apr 13

PMID : 21490226






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Here, we further investigated their physiological role: in epitope mapping studies, NAbs-Abeta recognized the mid-/C-terminal end of Abeta and preferentially bound to oligomers but failed to bind to monomers/fibrils. nabs amyloid beta (A4) precursor protein Mus musculus
2 Here, we further investigated their physiological role: in epitope mapping studies, NAbs-Abeta recognized the mid-/C-terminal end of Abeta and preferentially bound to oligomers but failed to bind to monomers/fibrils. nabs amyloid beta (A4) precursor protein Mus musculus
3 NAbs-Abeta were able to interfere with Abeta peptide toxicity, but NAbs-Abeta did not readily clear senile plaques although early fleecy-like plaques were reduced. nabs amyloid beta (A4) precursor protein Mus musculus
4 NAbs-Abeta were able to interfere with Abeta peptide toxicity, but NAbs-Abeta did not readily clear senile plaques although early fleecy-like plaques were reduced. nabs amyloid beta (A4) precursor protein Mus musculus
5 NAbs-Abeta were able to interfere with Abeta peptide toxicity, but NAbs-Abeta did not readily clear senile plaques although early fleecy-like plaques were reduced. nabs amyloid beta (A4) precursor protein Mus musculus