Title : Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.

Pub. Date : 2011 May 1

PMID : 21482471






1 Functional Relationships(s)
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1 The most potent inhibitors of CYP1-EROD activity were the methoxylated flavones acacetin, diosmetin, eupatorin and the di-hydroxylated flavone chrysin, indicating that the 4"-OCH(3) group at the B ring and the 5,7-dihydroxy motif at the A ring play a prominent role in EROD inhibition. Flavones cytochrome P450 family 1 subfamily A member 1 Homo sapiens