Title : Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.

Pub. Date : 2011 May

PMID : 21478880






1 Functional Relationships(s)
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1 We show that the saturated fatty acid palmitate, but not unsaturated oleate, induces the activation of the NLRP3-ASC inflammasome, causing caspase-1, IL-1beta and IL-18 production. saturated fatty acid palmitate interleukin 18 Homo sapiens