Title : Involvement of Rho-kinase in TGF-β-stimulated heat shock protein 27 induction in osteoblasts.

Pub. Date : 2009 Sep-Oct

PMID : 21475886






2 Functional Relationships(s)
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1 In addition, we recently reported that the Rho-kinase inhibitors Y27632 and fasudil suppressed the TGF-beta-induced phosphorylation of SAPK/JNK, but not p44/p42 MAP kinase, p38 MAP kinase or Smad2. Y 27632 transforming growth factor, beta 1 Mus musculus
2 Y27632 and fasudil significantly suppressed the HSP27 induction stimulated by TGF-beta in a dose-dependent manner, without affecting the protein levels of HSP70 or HSP90. Y 27632 transforming growth factor, beta 1 Mus musculus