Title : Mitochondrial diabetes and deafness: possible dysfunction of strial marginal cells of the inner ear.

Pub. Date : 2011 Apr

PMID : 21453644






1 Functional Relationships(s)
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1 CONCLUSIONS: The m.3243A>G mutation not only underlies a dysfunction of the insulin-producing beta cell of the pancreas but also results in a reduction in adenosine triphosphate production of the strial marginal cells of the inner ear, thus diminishing the energy (in the form of potassium ion gradient) needed for the outer hair cells of the organ of Corti to amplify the soundwaves, particularly at high frequencies. Potassium insulin Homo sapiens