Title : Hydroxycamptothecin-loaded Fe3O4 nanoparticles induce human lung cancer cell apoptosis through caspase-8 pathway activation and disrupt tight junctions.

Pub. Date : 2011 Jun

PMID : 21435100






1 Functional Relationships(s)
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1 HCPT-loaded nanoparticles reduced the expression of cell-cell junction protein claudins, E-cadherin and ZO-1, and transmission electron microcopy demonstrated a disrupted tight junction ultrastructure. 10-hydroxycamptothecin tight junction protein 1 Homo sapiens