Title : Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells.

Pub. Date : 2011 Sep

PMID : 21418191






1 Functional Relationships(s)
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1 siRNA for Atg 5 or pharmacological block of p53 abolished fangchinoline-induced autophagy and inhibition of autophagy switched cell death to apoptosis in these cells, suggesting that cell death is irreversible once autophagy is induced by fangchinoline. fangchinoline autophagy related 5 Homo sapiens