Pub. Date : 2011 Nov
PMID : 21417583
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Therefore, we investigated the effects of AZM on IL-8 production in an oral epithelial cell line. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
2 | RESULTS: IL-8 mRNA expression, IL-8 production, and NF-kappaB activation in LPS-stimulated KB cells were inhibited by the addition of AZM. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
3 | RESULTS: IL-8 mRNA expression, IL-8 production, and NF-kappaB activation in LPS-stimulated KB cells were inhibited by the addition of AZM. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |
4 | CONCLUSIONS: This study suggests that AZM inhibits LPS-induced IL-8 production in an oral epithelial cell line, in part caused by the suppression of Rac1 and NF-kappaB activation. | Azithromycin | C-X-C motif chemokine ligand 8 | Homo sapiens |