PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21417583-4 2011 Therefore, we investigated the effects of AZM on IL-8 production in an oral epithelial cell line. Azithromycin 42-45 C-X-C motif chemokine ligand 8 Homo sapiens 49-53 21417583-8 2011 RESULTS: IL-8 mRNA expression, IL-8 production, and NF-kappaB activation in LPS-stimulated KB cells were inhibited by the addition of AZM. Azithromycin 134-137 C-X-C motif chemokine ligand 8 Homo sapiens 9-13 21417583-8 2011 RESULTS: IL-8 mRNA expression, IL-8 production, and NF-kappaB activation in LPS-stimulated KB cells were inhibited by the addition of AZM. Azithromycin 134-137 C-X-C motif chemokine ligand 8 Homo sapiens 31-35 21417583-10 2011 CONCLUSIONS: This study suggests that AZM inhibits LPS-induced IL-8 production in an oral epithelial cell line, in part caused by the suppression of Rac1 and NF-kappaB activation. Azithromycin 38-41 C-X-C motif chemokine ligand 8 Homo sapiens 63-67