Title : Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture.

Pub. Date : 2011 Mar 1

PMID : 21390294






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mitochondrial Sirt3 was increased following PARP-1 mediated NAD depletion, which was reversed by either inhibition of PARP-1 or exogenous NAD. nadide sirtuin 3 Mus musculus
2 Mitochondrial Sirt3 was increased following PARP-1 mediated NAD depletion, which was reversed by either inhibition of PARP-1 or exogenous NAD. nadide sirtuin 3 Mus musculus
3 We found that massive reactive oxygen species (ROS) produced under this NAD depleted condition mediated the increase in mitochondrial Sirt3. nadide sirtuin 3 Mus musculus