Title : Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene.

Pub. Date : 2011 Apr 22

PMID : 21388966






2 Functional Relationships(s)
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1 Significantly, overexpression of Nampt gene reduced, whereas knockdown increased, hepatic triglyceride levels in vitro and in vivo. Triglycerides nicotinamide phosphoribosyltransferase Mus musculus
2 Thus, FoxOs control the Nampt gene expression and the NAD(+) signaling in the regulation of hepatic triglyceride homeostasis. Triglycerides nicotinamide phosphoribosyltransferase Mus musculus