Protein Name nicotinamide phosphoribosyltransferase
Organism Mus musculus
Gene ID 59027
Gene Symbol

Nampt

UniProt Q99KQ4 (NAMPT_MOUSE)
Relationships Total Number of functionally related compound(s) : 156
Total Number of Articles : 220
Description

nicotinamide phosphoribosyltransferase

Gene Summary

Enables identical protein binding activity and nicotinamide phosphoribosyltransferase activity. Involved in circadian regulation of gene expression; nicotinamide metabolic process; and nicotinamide nucleotide biosynthetic process. Acts upstream of or within NAD+ biosynthetic process. Located in cytoplasm. Is active in cytosol and mitochondrial matrix. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • nicotinamide phosphoribosyltransferase
  • pre-B-cell colony-enhancing factor 1 homolog
  • 1110035O14Rik
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Properties