Title : Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone.

Pub. Date : 2011 Apr 18

PMID : 21384861






1 Functional Relationships(s)
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1 In studies using 1,2-naphthoquinone (1,2-NQ) as a model quinone, we found that Keap1, the negative regulator of Nrf2, was readily arylated at its reactive thiols by 1,2-NQ. quinone kelch-like ECH-associated protein 1 Mus musculus